Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.46 |
| ▸ | CTSD | P07339 | 7/20 | 0.44 |
| ▸ | CTSB | P07858 | 4/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333273 | 0.92 | REN (0.44) | RENCTSDCTSBCTSKCYP3A4 | |
| SCHEMBL7329720 | 0.90 | CTSB (0.53) | RENCTSDCTSBCTSK | |
| SCHEMBL10378645 | 0.89 | REN (0.44) | RENCTSDCTSBCTSKCYP3A4 | |
| SCHEMBL7332055 | 0.85 | CTSD (0.39) | RENCTSD | |
| SCHEMBL7330377 | 0.80 | CTRB1 (0.43) | CTSBCTSKCYP3A4 | |
| SCHEMBL7333276 | 0.79 | REN (0.53) | RENCTSD | |
| SCHEMBL30601624 | 0.79 | CYP3A4 (0.55) | RENCTSDCTSBCTSKCYP3A4 | |
| SCHEMBL7329712 | 0.79 | REN (0.52) | RENCTSDELANE | |
| SCHEMBL7329705 | 0.78 | CTSD (0.40) | CTSDCYP3A4 | |
| SCHEMBL7329730 | 0.76 | CTSD (0.58) | RENCTSDCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |