Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 7/20 | 0.53 |
| ▸ | CTSK | P43235 | 7/20 | 0.53 |
| ▸ | REN | P00797 | 4/20 | 0.45 |
| ▸ | CTSD | P07339 | 3/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333273 | 0.91 | REN (0.44) | CTSBCTSKRENCTSD | |
| SCHEMBL7320456 | 0.90 | REN (0.46) | CTSBCTSKRENCTSD | |
| SCHEMBL10378645 | 0.88 | REN (0.44) | CTSBCTSKRENCTSD | |
| SCHEMBL7324603 | 0.83 | CTSD (0.42) | CTSBCTSKRENCTSD | |
| SCHEMBL7330377 | 0.83 | CTRB1 (0.43) | CTSBCTSK | |
| SCHEMBL7329730 | 0.81 | CTSD (0.58) | CTSBCTSKRENCTSDKLK5 | |
| SCHEMBL30601624 | 0.80 | CYP3A4 (0.55) | CTSBCTSKRENCTSD | |
| SCHEMBL7324608 | 0.80 | CTSD (0.57) | CTSBCTSKRENCTSDKLK5 | |
| SCHEMBL30748713 | 0.79 | CTSK (0.65) | CTSBCTSKRENCTSDTRPM8 | |
| SCHEMBL7329209 | 0.79 | CTSD (0.64) | CTSBCTSKRENCTSDKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |