Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7320760

CCOC(=O)c1ccc(-c2cn3nc(-c4ccccc4N4CC(C)OC(C)C4)sc3n2)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 4/20 0.40
HPGD P15428 3/20 0.40
LMNA P02545 1/20 0.40
RARA P10276 1/20 0.38
RARB P10826 1/20 0.38
RARG P13631 1/20 0.38
TP53 P04637 4/20 0.37
PDK2 Q15119 1/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
KDM4E B2RXH2 2/20 0.36
HSD17B10 Q99714 1/20 0.36
DPP4 P27487 1/20 0.36
DPP7 Q9UHL4 1/20 0.36
MAPT P10636 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7320765 1.00 ALDH1A1 (0.44) ALDH1A1L3MBTL1MEN1GAAKMT2A
Trifluoroacetic Acid SCHEMBL6539243 0.81 TP53 (0.56) SMN1; SMN2RARARARBRARGTP53
Trifluoroacetic Acid SCHEMBL6132991 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1MEN1GAAKMT2A
Trifluoroacetic Acid SCHEMBL7323148 0.77 LMNA (0.48) ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2
Trifluoroacetic Acid SCHEMBL7323795 0.77 CA12 (0.56) ALDH1A1SMN1; SMN2HPGDRARARARB
Trifluoroacetic Acid SCHEMBL7325659 0.76 SIRT2 (0.46) ALDH1A1L3MBTL1GAAHPGDLMNA
Trifluoroacetic Acid SCHEMBL6538546 0.76 MAPT (0.53) ALDH1A1RARARARBRARGTP53
Trifluoroacetic Acid SCHEMBL7324043 0.76 MTOR (0.42) L3MBTL1MEN1KMT2ALMNARARA
Trifluoroacetic Acid SCHEMBL7317609 0.75 TP53 (0.41) ALDH1A1LMNARARARARBRARG
Trifluoroacetic Acid SCHEMBL7318099 0.74 F2RL3 (0.41) RARARARBRARGTP53DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6232290-B1 FUNGICIDES AGAINST PNEUMOCYSTIS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-05-15 US disclosed