Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.48 |
| ▸ | MMP9 | P14780 | 6/20 | 0.48 |
| ▸ | MMP13 | P45452 | 5/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 9/20 | 0.47 |
| ▸ | MMP3 | P08254 | 9/20 | 0.47 |
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325126 | 0.87 | MMP1 (0.47) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL7320834 | 0.80 | MMP1 (0.49) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL7320832 | 0.73 | MMP1 (0.50) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL28637487 | 0.71 | PPARA (0.48) | HSD17B10LMNAKDM4EALDH1A1TSHR | |
| SCHEMBL28281237 | 0.70 | ALDH1A1 (0.48) | HSD17B10LMNAKDM4EALDH1A1TSHR | |
| SCHEMBL7320836 | 0.69 | MMP9 (0.39) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL7325114 | 0.69 | MMP1 (0.48) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL7325109 | 0.67 | MMP1 (0.49) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL7351595 | 0.67 | MMP1 (0.47) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL7207041 | 0.66 | MMP1 (0.61) | MMP1MMP9MMP13ADAM17MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |