SCHEMBL732143

SCHEMBL732143

C(OCC1CO1)C1CO1.CC(C)C(O)C(C)(C)CO

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
MAPK1 P28482 1/20 0.46
ALDH1A1 P00352 7/20 0.40
SMN1; SMN2 Q16637 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
TP53 P04637 2/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP1A2 P05177 1/20 0.35
PPARG P37231 1/20 0.35
HIF1A Q16665 1/20 0.35
TRPA1 O75762 1/20 0.31
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13593495 0.85 TSHR (0.56) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL9792620 0.80 TSHR (0.57) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL4461926 0.78 TSHR (0.59) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL9792647 0.78 TSHR (0.48) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL1946788 0.78 TSHR (0.52) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
Isopropyl Alcohol SCHEMBL27564110 0.78 TSHR (0.52) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL28046836 0.77 TSHR (0.53) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
Propylene Glycol SCHEMBL40031 0.76 TSHR (0.47) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
Propylene Glycol SCHEMBL2120984 0.76 TSHR (0.47) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL7725829 0.76 TSHR (0.63) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8889802-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2014-11-18 US disclosed
US-8765984-B2 Methods and systems for making thiol compounds from terminal olefinic compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-07-01 US disclosed
US-20120232297-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-09-13 US disclosed
US-20120130040-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2012-05-24 US disclosed
EP-2448990-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME Polymeright Inc. (US) 2012-05-09 EP disclosed
US-8138278-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2012-03-20 US disclosed
US-20110152492-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2011-06-23 US disclosed
US-7910666-B2 Mercaptan-hardened epoxy polymer compositions and processes for making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-03-22 US disclosed
WO-2011008480-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME POLYMERIGHT, INC. (US) 2011-01-20 WO disclosed
US-20090264669-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2009-10-22 US disclosed
EP-1940992-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2008-07-09 EP disclosed
US-20070112100-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2007-05-17 US disclosed
WO-2007022217-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-02-22 WO disclosed
US-5958663-A MAGENTA COUPER AND STABILIZER CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-09-28 US disclosed
US-5763144-A MAGENTA COUPLERS WITH HETEROCYCLIC ESTER STABILIZERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-06-09 US disclosed
WO-1995022082-A1 COLOUR-PHOTOGRAPHIC RECORDING MATERIAL CIBA-GEIGY AG (CH) 1995-08-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120232297-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds TST, HHAT, GSTO1 TSHR 4571/4885MAPK1 3600/4885ALDH1A1 157/4885
US-20090264669-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds TST, HHAT, GSTO1 TSHR 4571/4885MAPK1 3600/4885ALDH1A1 157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.