Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322262 | 0.90 | LMNA (0.43) | ALDH1A1KDM4EL3MBTL1MMP2HTT | |
| SCHEMBL7317430 | 0.83 | MMP9 (0.44) | KMT2AALDH1A1KDM4EMMP2MEN1 | |
| SCHEMBL7318787 | 0.83 | MMP13 (0.48) | ALDH1A1MMP2 | |
| SCHEMBL7311156 | 0.83 | KDM4E (0.44) | KMT2AALDH1A1KDM4EPOLBMMP2 | |
| SCHEMBL7316579 | 0.81 | KDM4E (0.44) | KMT2AALDH1A1KDM4ETDP1MMP2 | |
| SCHEMBL7317521 | 0.81 | MMP13 (0.41) | KMT2AKDM4ETDP1MMP2NAMPT | |
| SCHEMBL7322032 | 0.80 | MMP13 (0.40) | ALDH1A1KDM4EL3MBTL1MMP2NAMPT | |
| SCHEMBL7316215 | 0.79 | MMP13 (0.41) | ALDH1A1KDM4EPOLBMMP2NAMPT | |
| SCHEMBL7324047 | 0.79 | GABRG2 (0.42) | KMT2AMMP2MEN1 | |
| SCHEMBL7319136 | 0.79 | SMN1; SMN2 (0.40) | KMT2AALDH1A1KDM4EPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |