Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 17/20 | 0.68 |
| ▸ | SIRT1 | Q96EB6 | 12/20 | 0.68 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.61 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.56 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750042 | 1.00 | SIRT2 (0.68) | SIRT2SIRT1SIRT3CAPN1CAPN2 | |
| SCHEMBL29055302 | 0.87 | SIRT2 (0.81) | SIRT2SIRT1SIRT3 | |
| SCHEMBL29055304 | 0.87 | SIRT2 (0.81) | SIRT2SIRT1SIRT3 | |
| SCHEMBL23519310 | 0.87 | SIRT2 (0.81) | SIRT2SIRT1SIRT3 | |
| SCHEMBL7414295 | 0.87 | CAPN1 (0.60) | SIRT2SIRT1CAPN1CAPN2CTSL | |
| SCHEMBL7689520 | 0.83 | SIRT2 (0.76) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL4787188 | 0.83 | SIRT2 (0.76) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL21357647 | 0.83 | SIRT2 (0.76) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL2963543 | 0.83 | SIRT2 (0.76) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL671485 | 0.83 | SIRT2 (0.65) | SIRT2SIRT1SIRT3CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580923-B2 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | NORTHWESTERN UNIVERSITY (US) | 2013-11-12 | — | — | US | disclosed |
| US-20120264912-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2012-10-18 | — | — | US | disclosed |
| US-8138140-B2 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | NORTHWESTERN UNIVERSITY (US) | 2012-03-20 | — | — | US | disclosed |
| EP-1696945-B1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | UNIV NORTHWESTERN (US) | 2012-01-18 | — | — | EP | disclosed |
| EP-2314305-A2 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | Northwestern University (US) | 2011-04-27 | — | — | EP | disclosed |
| US-20090269847-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2009-10-29 | — | — | US | disclosed |
| US-20090269847-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2009-10-29 | — | — | US | disclosed |
| US-7544661-B2 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | NORTHWESTERN UNIVERSITY (US) | 2009-06-09 | — | — | US | disclosed |
| EP-1696945-A4 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | UNIV NORTHWESTERN (US) | 2007-03-21 | — | — | EP | disclosed |
| EP-1696945-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2006-09-06 | — | — | EP | disclosed |
| US-20050209145-A1 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | ENERGY, UNITED STATES DEPARTMENT OF | 2005-09-22 | — | — | US | disclosed |
| WO-2005056039-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090269847-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | HDGF, HDGFL3, IAPP | SIRT2 4805/4885SIRT1 4787/4885SIRT3 4826/4885 |
| US-20120264912-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | HDGF, HDGFL3, IAPP | SIRT2 4805/4885SIRT1 4787/4885SIRT3 4826/4885 |
| US-20050209145-A1 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | HDGF, HDGFL3, IAPP | SIRT2 4805/4885SIRT1 4787/4885SIRT3 4826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.