Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322359 | 1.00 | ACHE (0.44) | ACHELMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL7316108 | 0.85 | KIF11 (0.45) | KMT2AKIF11 | |
| SCHEMBL7316115 | 0.85 | KIF11 (0.45) | KMT2AKIF11 | |
| SCHEMBL7325936 | 0.84 | KMT2A (0.41) | ACHEKMT2AMEN1ALDH1A1KIF11 | |
| SCHEMBL7325931 | 0.84 | KMT2A (0.41) | ACHEKMT2AMEN1ALDH1A1KIF11 | |
| SCHEMBL7323867 | 0.84 | KIF11 (0.44) | KMT2AMEN1ALDH1A1KIF11CYP1A2 | |
| SCHEMBL7317367 | 0.84 | KIF11 (0.44) | KMT2AMEN1ALDH1A1KIF11CYP1A2 | |
| SCHEMBL7317362 | 0.84 | KIF11 (0.44) | KMT2AMEN1ALDH1A1KIF11CYP1A2 | |
| SCHEMBL7323759 | 0.84 | KIF11 (0.37) | L3MBTL1KIF11AKR1C3AKR1C2 | |
| SCHEMBL7323752 | 0.84 | KIF11 (0.37) | L3MBTL1KIF11AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |