Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | MASP2 | O00187 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332144 | 1.00 | CASP1 (0.34) | CASP1MASP2F2 | |
| SCHEMBL7332732 | 1.00 | CASP1 (0.34) | CASP1MASP2F2 | |
| SCHEMBL7322873 | 0.94 | CES1 (0.35) | — | |
| SCHEMBL7324394 | 0.90 | TPSAB1 (0.40) | CASP1 | |
| SCHEMBL7329315 | 0.89 | ALOX5 (0.37) | — | |
| SCHEMBL7329240 | 0.89 | CTSL (0.38) | CASP1 | |
| SCHEMBL7324594 | 0.89 | CTSL (0.38) | CASP1 | |
| SCHEMBL7329470 | 0.89 | CTSS (0.32) | — | |
| SCHEMBL7322952 | 0.89 | CTSS (0.32) | — | |
| SCHEMBL7323129 | 0.87 | ERAP2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |