Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7322678 | 0.99 | SIGMAR1 (0.44) | HRH3ACHEKCNH2SIGMAR1SLC6A2 | |
| SCHEMBL7325971 | 0.84 | KDM4E (0.60) | HRH3SIGMAR1SLC6A4 | |
| Hydrochloric Acid SCHEMBL5881222 | 0.83 | KDM4E (0.59) | HRH3SIGMAR1SLC6A4 | |
| SCHEMBL7321964 | 0.82 | HRH3 (0.64) | HRH3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL5082574 | 0.82 | KDM4E (0.58) | HRH3SIGMAR1SLC6A4 | |
| SCHEMBL7326091 | 0.81 | HRH3 (0.67) | HRH3 | |
| Hydrochloric Acid SCHEMBL27431543 | 0.81 | SIGMAR1 (0.64) | HRH3SIGMAR1 | |
| SCHEMBL7324710 | 0.81 | HRH3 (0.51) | HRH3KCNH2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9528342 | 0.81 | HRH3 (0.65) | HRH3 | |
| SCHEMBL7317615 | 0.80 | ALDH1A1 (0.59) | HRH3KCNH2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542846-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |
| WO-1992002502-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | claimed |