Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 3/20 | 0.51 |
| ▸ | TGM2 | P21980 | 3/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329311 | 0.84 | ALDH1A1 (0.53) | MEN1ALDH1A1KMT2ASMN1; SMN2REN | |
| SCHEMBL9498688 | 0.84 | FOLH1 (0.67) | MMP2MMP9FOLH1CPB1CPB2 | |
| SCHEMBL9556385 | 0.80 | ALDH1A1 (0.58) | MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL17073781 | 0.78 | CTSL (0.63) | MMP2MMP9FOLH1CA1CA2 | |
| SCHEMBL10771246 | 0.77 | FOLH1 (0.62) | MMP2MMP9FOLH1CPB1CPB2 | |
| SCHEMBL9495193 | 0.77 | CA1 (0.63) | FOLH1CA1CA2CPB1CPB2 | |
| Hydrochloric Acid SCHEMBL9319023 | 0.76 | FOLH1 (0.53) | FOLH1CA1CA2CPB1CPB2 | |
| Hydrochloric Acid SCHEMBL9494357 | 0.76 | CA1 (0.62) | FOLH1CA1CA2CPB1CPB2 | |
| SCHEMBL7359178 | 0.75 | DPP8 (0.46) | TGM2FOLH1RENDPP8DPP7 | |
| SCHEMBL1509765 | 0.75 | CPB1 (0.70) | MMP2MMP9FOLH1CPB1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198426-A | RENIN INHIBITORS CONTAINING C-TERMINAL DIHYDROXY AMIDES | WARNER-LAMBERT COMPANY (US) | 1993-03-30 | — | — | US | disclosed |
| WO-1990007521-A1 | RENIN INHIBITORS CONTAINING C-TERMINAL DIHYDROXY AMIDES | WARNER-LAMBERT COMPANY (US) | 1990-07-12 | — | — | WO | disclosed |