Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.70 |
| ▸ | HTR2A | P28223 | 6/20 | 0.70 |
| ▸ | HTR2C | P28335 | 5/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.70 |
| ▸ | MPO | P05164 | 1/20 | 0.70 |
| ▸ | HTR1D | P28221 | 12/20 | 0.68 |
| ▸ | HTR1B | P28222 | 9/20 | 0.68 |
| ▸ | HTR2B | P41595 | 4/20 | 0.67 |
| ▸ | HTR7 | P34969 | 4/20 | 0.67 |
| ▸ | HTR5A | P47898 | 4/20 | 0.67 |
| ▸ | HTR6 | P50406 | 4/20 | 0.67 |
| ▸ | HTR1E | P28566 | 3/20 | 0.67 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.67 |
| ▸ | HTR3B | O95264 | 2/20 | 0.67 |
| ▸ | HTR1F | P30939 | 2/20 | 0.67 |
| ▸ | HTR3A | P46098 | 2/20 | 0.67 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.67 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.67 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633081 | 1.00 | HTR1A (0.70) | HTR1AHTR2AHTR2CSLC6A4MPO | |
| SCHEMBL6943874 | 0.89 | HTR1A (0.58) | HTR1AHTR2AHTR2CSLC6A4MPO | |
| SCHEMBL7324823 | 0.88 | HTR1D (0.68) | HTR1AHTR2AHTR2CSLC6A4MPO | |
| SCHEMBL15701982 | 0.87 | HTR2A (0.70) | HTR1AHTR2AHTR2CSLC6A4MPO | |
| SCHEMBL9169192 | 0.87 | HTR7 (0.67) | HTR1AHTR2AHTR2CSLC6A4MPO | |
| SCHEMBL6942952 | 0.87 | HTR1A (0.56) | HTR1AHTR2AHTR2CSLC6A4MPO | |
| SCHEMBL24243715 | 0.86 | HTR2A (0.72) | HTR1AHTR2AHTR2CSLC6A4MPO | |
| SCHEMBL30916158 | 0.85 | HTR1D (0.60) | HTR1AHTR2AHTR2CSLC6A4MPO | |
| SCHEMBL8869593 | 0.84 | HTR1D (0.71) | HTR1AHTR2AHTR2CSLC6A4MPO | |
| SCHEMBL8785993 | 0.84 | HTR1D (0.55) | HTR1AHTR2AHTR2CSLC6A4MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730124-A4 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORP (US) | 2009-04-01 | — | — | EP | claimed |
| EP-1730124-A1 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Amphora Discovery Corporation (US) | 2006-12-13 | — | — | EP | claimed |
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | claimed |
| WO-2005097758-A1 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-10-20 | — | — | WO | claimed |
| US-20260090957-A1 | Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness | DRESDNER JR KARL P (US) | 2026-04-02 | — | — | US | disclosed |
| US-20250339403-A1 | Tryptamine Formulations and Uses Thereof | Natural MedTech Pty Ltd (AU) | 2025-11-06 | — | — | US | disclosed |
| EP-4615444-A1 | TRYPTAMINE FORMULATIONS AND USES THEREOF | Natural Medtech Pty Ltd (AU) | 2025-09-17 | — | — | EP | disclosed |
| US-12303564-B2 | Composite chitosan-tannin-active agent compositions and methods of making and using same | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-05-20 | — | — | US | disclosed |
| US-12295916-B2 | Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness | DRESDNER JR KARL P (US) | 2025-05-13 | — | — | US | disclosed |
| US-20240228440-A1 | ORGANIC COMPOUND SALTS | GH Research Ireland Limited (IE) | 2024-07-11 | — | — | US | disclosed |
| WO-2024098098-A1 | TRYPTAMINE FORMULATIONS AND USES THEREOF | Natural MedTech Pty Ltd (AU) | 2024-05-16 | — | — | WO | disclosed |
| WO-2024074850-A1 | A TREATMENT FOR MENTAL DISORDERS | ReWire Therapeutics Limited (GB) | 2024-04-11 | — | — | WO | disclosed |
| US-20130129812-A1 | NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-05-23 | — | — | US | disclosed |
| US-20100217013-A1 | ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF ZOLMITRIPTAN | CHIRAL QUEST, INC. | 2010-08-26 | — | — | US | disclosed |
| EP-1751104-B1 | SYNTHESIS METHODS AND INTERMEDIATES FOR THE MANUFACTURE OF RIZATRIPTAN | RATIOPHARM GMBH (DE) | 2010-03-24 | — | — | EP | disclosed |
| WO-2010010000-A2 | SCREENING METHOD, DIAGNOSTIC METHOD AND SMALL NUCLEIC ACID FOR THE TREATMENT OF CNS DISORDERS | KAROLINSKA INNOVATIONS AB (SE) | 2010-01-28 | — | — | WO | disclosed |
| EP-1730124-A4 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORP (US) | 2009-04-01 | — | — | EP | disclosed |
| EP-1730124-A1 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Amphora Discovery Corporation (US) | 2006-12-13 | — | — | EP | disclosed |
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
| WO-2005097758-A1 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129812-A1 | NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER | HDGF, HCCS, CCNC | HTR1A 152/4885HTR2A 94/4885HTR2C 380/4885 |
| US-12295916-B2 | Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness | SLC38A7, QPCT, SLC18A3 | HTR1A 1984/4885HTR2A 2029/4885HTR2C 1330/4885 |
| US-20100217013-A1 | ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF ZOLMITRIPTAN | HTR5A, HTR3A, HTR2A | HTR1A 4/4885HTR2A 3/4885HTR2C 16/4885 |
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | HTR1A 3298/4885HTR2A 3380/4885HTR2C 2397/4885 |
| US-12303564-B2 | Composite chitosan-tannin-active agent compositions and methods of making and using same | TTPA, CHIA, CHIT1 | HTR1A 2312/4885HTR2A 2918/4885HTR2C 3495/4885 |
| US-20260090957-A1 | Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness | QPCT, SLC38A7, QPCTL | HTR1A 2572/4885HTR2A 2610/4885HTR2C 1076/4885 |
| US-20240228440-A1 | ORGANIC COMPOUND SALTS | HTR5A, HTR2B, HTR4 | HTR1A 17/4885HTR2A 11/4885HTR2C 4/4885 |
| US-20250339403-A1 | Tryptamine Formulations and Uses Thereof | MAOA, MAOB, TPH1 | HTR1A 15/4885HTR2A 17/4885HTR2C 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.