Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 4/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326123 | 0.94 | SYK (0.48) | SYKCTSDRENCTSKCTSB | |
| SCHEMBL7330386 | 0.83 | PSMB1 (0.42) | SYKCTSDRENCTSKPSMB1 | |
| SCHEMBL10378284 | 0.81 | LTA4H (0.45) | SYKRENPSMB1PSMB9PSMB8 | |
| SCHEMBL7323405 | 0.76 | SYK (0.46) | SYKCTSDRENCTSKCTSB | |
| SCHEMBL27292008 | 0.75 | ACE (0.58) | CTSDRENPSMB1PSMB9PSMB8 | |
| SCHEMBL24050025 | 0.74 | SYK (0.56) | SYKCTSKCTSBCTSSKLK5 | |
| SCHEMBL7324895 | 0.74 | LTA4H (0.40) | SYKPSMB1PSMB9PSMB8PSMB5 | |
| SCHEMBL8141342 | 0.74 | CTSK (0.56) | SYKCTSDCTSKCTSBCTSS | |
| SCHEMBL21684844 | 0.74 | CTSK (0.56) | SYKCTSDCTSKCTSBCTSS | |
| SCHEMBL6279109 | 0.74 | CTSK (0.56) | SYKCTSDCTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |