Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324896 | 1.00 | ESR1 (0.43) | ESR1ESR2KIF11TDP1KMT2A | |
| SCHEMBL7317367 | 0.86 | KIF11 (0.44) | KIF11TDP1KMT2AMAPTMEN1 | |
| SCHEMBL7323867 | 0.86 | KIF11 (0.44) | KIF11TDP1KMT2AMAPTMEN1 | |
| SCHEMBL7317362 | 0.86 | KIF11 (0.44) | KIF11TDP1KMT2AMAPTMEN1 | |
| SCHEMBL7315698 | 0.86 | SLC1A3 (0.43) | KIF11CYP1A2CYP2C19PDK2HIF1A | |
| SCHEMBL7315704 | 0.86 | SLC1A3 (0.43) | KIF11CYP1A2CYP2C19PDK2HIF1A | |
| SCHEMBL7322359 | 0.84 | ACHE (0.44) | KIF11KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL7322362 | 0.84 | ACHE (0.44) | KIF11KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL7325808 | 0.84 | KIF11 (0.38) | ESR1ESR2KIF11TDP1KMT2A | |
| SCHEMBL7325812 | 0.84 | KIF11 (0.38) | ESR1ESR2KIF11TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |