Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 6/20 | 0.46 |
| ▸ | CA1 | P00915 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA9 | Q16790 | 6/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ENPP3 | O14638 | 5/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337064 | 0.83 | F2 (0.46) | ALDH1A1SMN1; SMN2ENPP3ENPP1ENPP2 | |
| SCHEMBL7335262 | 0.82 | GRK2 (0.49) | FAAHALDH1A1MAPK1MEN1LMNA | |
| SCHEMBL22187323 | 0.81 | CA2 (0.57) | FAAHCA12CA1CA2CA9 | |
| SCHEMBL29620069 | 0.81 | CA2 (0.57) | FAAHCA12CA1CA2CA9 | |
| SCHEMBL22446482 | 0.80 | MAPT (0.60) | FAAHCA12CA1CA2CA9 | |
| SCHEMBL5287709 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTMAPK1LMNAPOLB | |
| SCHEMBL29274193 | 0.79 | FAAH (0.51) | FAAHCA12CA1CA2CA9 | |
| SCHEMBL29673712 | 0.79 | FAAH (0.51) | FAAHCA12CA1CA2CA9 | |
| SCHEMBL3008207 | 0.78 | FAAH (0.51) | FAAHCA12CA1CA2CA9 | |
| SCHEMBL11521888 | 0.78 | CA1 (0.60) | FAAHCA1CA2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046710-C | New 4-aminopyridines, process for preparing the same and medicaments containing the same | LUOHE DIAGNOSTIC EQUIPMENT CO (DE) | 1999-11-24 | — | — | CN | disclosed |
| CN-1119858-A | Aminopyridines, process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1996-04-03 | — | — | CN | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |