Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK2 | P25098 | 10/20 | 0.49 |
| ▸ | GRK3 | P35626 | 9/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GRK5 | P34947 | 3/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543121 | 0.83 | F2 (0.61) | FAAHF2MAPK1ALDH1A1 | |
| SCHEMBL7334463 | 0.83 | LMNA (0.67) | LMNATSHRMAPK1L3MBTL1MEN1 | |
| SCHEMBL7324955 | 0.82 | FAAH (0.50) | LMNAFAAHMAPK1ALDH1A1MEN1 | |
| SCHEMBL8547282 | 0.81 | KMT2A (0.56) | GRK2GRK3LMNAF2ALDH1A1 | |
| SCHEMBL3008207 | 0.77 | FAAH (0.51) | FAAHMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL11521888 | 0.77 | CA1 (0.60) | LMNAFAAHMAPK1ALDH1A1MEN1 | |
| SCHEMBL22446482 | 0.77 | MAPT (0.60) | LMNAFAAHTSHRMAPK1MEN1 | |
| SCHEMBL22187323 | 0.75 | CA2 (0.57) | LMNAFAAHTSHRMAPK1ALDH1A1 | |
| SCHEMBL29620069 | 0.75 | CA2 (0.57) | LMNAFAAHTSHRMAPK1ALDH1A1 | |
| SCHEMBL7336072 | 0.74 | LMNA (0.59) | LMNAF2MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046710-C | New 4-aminopyridines, process for preparing the same and medicaments containing the same | LUOHE DIAGNOSTIC EQUIPMENT CO (DE) | 1999-11-24 | — | — | CN | disclosed |
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| CN-1119858-A | Aminopyridines, process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1996-04-03 | — | — | CN | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |