Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | APLNR | P35414 | 3/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460737 | 0.89 | PPARG (0.40) | PPARGACHEAPLNRAGTR1ESR2 | |
| SCHEMBL3459617 | 0.82 | ACHE (0.40) | PPARGACHEAPLNRAGTR1ESR2 | |
| SCHEMBL8070880 | 0.79 | XDH (0.36) | PPARGACHEAPLNRAGTR1AGTR2 | |
| SCHEMBL6534773 | 0.73 | BRS3 (0.54) | AGTR1AGTR2BRS3 | |
| SCHEMBL6534662 | 0.71 | BRS3 (0.48) | AGTR1AGTR2BRS3 | |
| SCHEMBL7050688 | 0.71 | AGTR1 (0.34) | PPARGAGTR1AGTR2BRS3 | |
| SCHEMBL7657853 | 0.69 | PPARG (0.39) | PPARGACHEAPLNRAGTR1ESR2 | |
| SCHEMBL9025753 | 0.68 | AGTR1 (0.42) | PPARGACHEAPLNRAGTR1ESR2 | |
| SCHEMBL9205903 | 0.67 | BRS3 (0.43) | AGTR1AGTR2BRS3 | |
| SCHEMBL7659925 | 0.67 | ACHE (0.43) | PPARGACHEAPLNRAGTR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |