SCHEMBL732544

SCHEMBL732544

CCOC(=O)C(C)Oc1ccc(-c2ncc(Cl)cc2Cl)cc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 5/20 0.41
MAPT P10636 4/20 0.41
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 4/20 0.39
HPGD P15428 1/20 0.39
GAA P10253 3/20 0.37
TSHR P16473 2/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
PPOX P50336 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
GPR55 Q9Y2T6 1/20 0.36
GPR119 Q8TDV5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11601818 0.90 L3MBTL1 (0.39) L3MBTL1TDP1MEN1KMT2AALDH1A1
SCHEMBL6907325 0.89 L3MBTL1 (0.48) L3MBTL1TDP1MEN1KMT2AALDH1A1
SCHEMBL8511664 0.89 L3MBTL1 (0.40) L3MBTL1TDP1MEN1KMT2AALDH1A1
SCHEMBL10515743 0.89 L3MBTL1 (0.40) L3MBTL1TDP1MEN1KMT2AALDH1A1
SCHEMBL10760195 0.89 ALDH1A1 (0.40) L3MBTL1TDP1MEN1KMT2AALDH1A1
SCHEMBL6732935 0.87 TSHR (0.47) L3MBTL1KMT2AALDH1A1LMNASMN1; SMN2
SCHEMBL9763694 0.87 TSHR (0.47) L3MBTL1KMT2AALDH1A1LMNASMN1; SMN2
SCHEMBL10510541 0.87 ALDH1A1 (0.38) L3MBTL1TDP1MEN1KMT2AALDH1A1
SCHEMBL731517 0.87 L3MBTL1 (0.39) L3MBTL1TDP1MEN1KMT2AALDH1A1
SCHEMBL11623239 0.87 SMN1; SMN2 (0.40) L3MBTL1TDP1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330904-B1 Herbicidal agent in the form of aqueous microemulsions HOECHST AG (DE) 1994-04-20 EP claimed
US-4973352-A Herbicidal agents in the form of aqueous transparent microemulsions HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-27 US claimed
EP-0330904-A1 Herbicidal agent in the form of aqueous microemulsions HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-06 EP claimed
EP-0154153-A1 Use of aryloxy compounds as antidotes HOECHST AKTIENGESELLSCHAFT (DE) 1985-09-11 EP claimed
US-4046553-A HERBICIDAL COMPOUND, HERBICIDAL COMPOSITION CONTAINING THE SAME AND METHOD OF USE THEREOF ISHIHARA SANGYO KAISHA, LTD. (JA) 1977-09-06 US claimed
US-9801374-B2 Active compound combinations comprising carboxamide derivatives BAYER CROPSCIENCE AG (DE) 2017-10-31 US disclosed
EP-1893016-B1 WATER-IN-OIL SUSPOEMULSIONS BAYER IP GMBH (DE) 2017-09-13 EP disclosed
EP-1651039-B1 OIL SUSPENSION CONCENTRATE CONTAINING DIFLUFENICAN BAYER IP GMBH (DE) 2017-01-04 EP disclosed
EP-1928232-B1 SOLID FORMULATION BAYER IP GMBH (DE) 2016-07-13 EP disclosed
US-20150245610-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2015-09-03 US disclosed
EP-2908639-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES Bayer Cropscience AG (DE) 2015-08-26 EP disclosed
US-9102623-B2 Pyridinecarboxamides, useful-plant-protecting composition comprising them and processes for their preparation and their use BAYER CROPSCIENCE AG (DE) 2015-08-11 US disclosed
US-4668276-A FOR HERBICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1987-05-26 US disclosed
US-4652666-A PLANT SAFENING AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-24 US disclosed
EP-0174562-A2 Plant protecting agents based on 1,2,4 - triazole derivatives as well as 1,2,4-triazole derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1986-03-19 EP disclosed
EP-0170905-A1 alpha-acyloximino-alkane-phosphonic(and -phosphinic) acid esters, their preparation and their use in plant protection HOECHST AKTIENGESELLSCHAFT (DE) 1986-02-12 EP disclosed
EP-0170906-A1 Plant-protecting agents based on oxime esters HOECHST AKTIENGESELLSCHAFT (DE) 1986-02-12 EP disclosed
EP-0154153-A1 Use of aryloxy compounds as antidotes HOECHST AKTIENGESELLSCHAFT (DE) 1985-09-11 EP disclosed
US-4414020-A AMIDOXIMES AS SAFENING AGENTS HOECHST AG (DE) 1983-11-08 US disclosed
US-4254262-A IN THE PRESENCE OF A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1981-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150245610-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES AADAC, PFAS, CBR3 L3MBTL1 1739/4885TDP1 1945/4885MEN1 4245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.