SCHEMBL7332387

SCHEMBL7332387

O=C(C1=CSC=CN1C(=O)C1CCc2ccccc2C1)C1C(=S)CN[C@@H]1C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 2/20 0.34
FAAH O00519 4/20 0.31
PLD2 O14939 1/20 0.31
PLD1 Q13393 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7322508 0.88 NR1D1 (0.32) IDH1FAAH
SCHEMBL7321288 0.87 IDH1 (0.33) IDH1FAAH
SCHEMBL7328709 0.82 PREP (0.35)
SCHEMBL7325825 0.79 P2RX7 (0.40) IDH1FAAHPLD2PLD1
SCHEMBL7324059 0.79 IDH1 (0.33) IDH1FAAH
SCHEMBL7301200 0.76 FAAH (0.38) IDH1FAAHPLD2PLD1
SCHEMBL7352616 0.74 FAAH (0.37) IDH1FAAH
SCHEMBL7320008 0.73 F2 (0.43)
SCHEMBL7316140 0.73 PREP (0.45)
SCHEMBL7323490 0.72 PREP (0.46) IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed