Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325843 | 1.00 | SLC6A4 (0.53) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| Oxalic Acid SCHEMBL7320957 | 0.95 | S1PR1 (0.51) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| Oxalic Acid SCHEMBL7320960 | 0.95 | S1PR1 (0.51) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| SCHEMBL7326607 | 0.83 | SLC6A4 (0.71) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| SCHEMBL7326600 | 0.83 | SLC6A4 (0.71) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| SCHEMBL7333002 | 0.81 | MCHR1 (0.51) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| SCHEMBL9528399 | 0.79 | MAOA (0.44) | KDM4EHRH3LMNABCL2A1 | |
| Oxalic Acid SCHEMBL7327873 | 0.79 | SLC6A4 (0.65) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| Oxalic Acid SCHEMBL7327867 | 0.79 | SLC6A4 (0.65) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| SCHEMBL9528392 | 0.79 | MAOA (0.44) | KDM4EHRH3LMNABCL2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542846-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |
| WO-1992002502-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | claimed |