Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326600 | 1.00 | SLC6A4 (0.71) | SLC6A4SLC6A3MAPTCYP2D6TDP1 | |
| Oxalic Acid SCHEMBL7327873 | 0.95 | SLC6A4 (0.65) | SLC6A4SLC6A3MEN1KMT2ASMN1; SMN2 | |
| Oxalic Acid SCHEMBL7327867 | 0.95 | SLC6A4 (0.65) | SLC6A4SLC6A3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7325847 | 0.83 | SLC6A4 (0.53) | SLC6A4SLC6A3SIGMAR1KDM4ES1PR1 | |
| SCHEMBL7325843 | 0.83 | SLC6A4 (0.53) | SLC6A4SLC6A3SIGMAR1KDM4ES1PR1 | |
| SCHEMBL7302397 | 0.79 | SLC6A3 (0.68) | SLC6A3CHRM4DRD2 | |
| SCHEMBL7333002 | 0.79 | MCHR1 (0.51) | SLC6A4SLC6A3MAPTSIGMAR1KDM4E | |
| Oxalic Acid SCHEMBL7320957 | 0.79 | S1PR1 (0.51) | SLC6A4SLC6A3MEN1KMT2ASMN1; SMN2 | |
| Oxalic Acid SCHEMBL7320960 | 0.79 | S1PR1 (0.51) | SLC6A4SLC6A3MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7321944 | 0.78 | SLC6A3 (0.67) | SLC6A3CHRM4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542846-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |
| CN-1061963-A | Be used as the croak pyridine class of the 4-replacement of medicine | SMITH KLINE FRENCH LAB (GB) | 1992-06-17 | — | — | CN | claimed |
| WO-1992002502-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | claimed |