Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528399 | 1.00 | MAOA (0.44) | MAOAACHEMAOBALDH1A1MCHR1 | |
| Oxalic Acid SCHEMBL9527661 | 0.96 | ALDH1A1 (0.48) | MAOAACHEMAOBALDH1A1MCHR1 | |
| Oxalic Acid SCHEMBL9527667 | 0.96 | ALDH1A1 (0.48) | MAOAACHEMAOBALDH1A1MCHR1 | |
| Oxalic Acid SCHEMBL9530842 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4ESMN1; SMN2LMNAHRH3 | |
| Oxalic Acid SCHEMBL9530845 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4ESMN1; SMN2LMNAHRH3 | |
| SCHEMBL7325843 | 0.79 | SLC6A4 (0.53) | KDM4ELMNABCL2A1HRH3 | |
| SCHEMBL7325847 | 0.79 | SLC6A4 (0.53) | KDM4ELMNABCL2A1HRH3 | |
| Oxalic Acid SCHEMBL7320957 | 0.77 | S1PR1 (0.51) | ALDH1A1MCHR1KDM4ESMN1; SMN2POLB | |
| Oxalic Acid SCHEMBL7320960 | 0.77 | S1PR1 (0.51) | ALDH1A1MCHR1KDM4ESMN1; SMN2POLB | |
| SCHEMBL9528092 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MCHR1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542844-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |
| CN-1062349-A | Be used as the croak pyridine class of the 3-replacement of medicine | SMITH KLINE FRENCH LAB (GB) | 1992-07-01 | — | — | CN | claimed |
| WO-1992002501-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | claimed |