Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | CCR3 | P51677 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7327867 | 1.00 | SLC6A4 (0.65) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| SCHEMBL7326600 | 0.95 | SLC6A4 (0.71) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| SCHEMBL7326607 | 0.95 | SLC6A4 (0.71) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| Oxalic Acid SCHEMBL7320957 | 0.85 | S1PR1 (0.51) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| Oxalic Acid SCHEMBL7320960 | 0.85 | S1PR1 (0.51) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| Oxalic Acid SCHEMBL7245307 | 0.81 | MCHR1 (0.49) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| Oxalic Acid SCHEMBL7245310 | 0.81 | MCHR1 (0.49) | SLC6A4SLC6A3S1PR1KDM4EHRH3 | |
| Oxalic Acid SCHEMBL9530845 | 0.80 | ALDH1A1 (0.52) | SLC6A4SLC6A3KDM4EHRH3CCR3 | |
| Oxalic Acid SCHEMBL9530842 | 0.80 | ALDH1A1 (0.52) | SLC6A4SLC6A3KDM4EHRH3CCR3 | |
| Oxalic Acid SCHEMBL7326226 | 0.80 | DRD2 (0.54) | SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559700-A1 | NOVEL PILOCARPINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | Santen Oy (FI) | 1993-09-15 | — | — | EP | disclosed |
| CN-1061963-A | Be used as the croak pyridine class of the 4-replacement of medicine | SMITH KLINE FRENCH LAB (GB) | 1992-06-17 | — | — | CN | disclosed |
| WO-1992009583-A1 | NOVEL PILOCARPINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | LEIRAS OY (FI) | 1992-06-11 | — | — | WO | disclosed |
| WO-1992002502-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |