Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.58 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.54 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4182645 | 0.89 | CPB1 (0.62) | CPB1CPB2SIRT1SIRT2SIRT3 | |
| SCHEMBL7322118 | 0.89 | SIRT2 (0.62) | CPB1CPB2SIRT1SIRT2SIRT3 | |
| SCHEMBL7322113 | 0.89 | SIRT2 (0.62) | CPB1CPB2SIRT1SIRT2SIRT3 | |
| Hydrochloric Acid SCHEMBL7982992 | 0.88 | SIRT2 (0.61) | CPB1CPB2SIRT1SIRT2SIRT3 | |
| SCHEMBL7374094 | 0.86 | CPB1 (0.55) | CPB1CPB2SIRT1SIRT2SIRT3 | |
| SCHEMBL7317571 | 0.85 | CTSL (0.60) | CPB1CPB2SIRT1SIRT2SIRT3 | |
| Trifluoroacetic Acid SCHEMBL7316577 | 0.84 | SIRT1 (0.57) | CPB1CPB2SIRT1SIRT2SIRT3 | |
| Trifluoroacetic Acid SCHEMBL9324388 | 0.84 | SIRT1 (0.57) | CPB1CPB2SIRT1SIRT2SIRT3 | |
| SCHEMBL19630958 | 0.83 | CTSK (0.50) | CPB1CPB2SIRT1SIRT2SIRT3 | |
| SCHEMBL30705372 | 0.80 | CPB1 (0.57) | CPB1CPB2SIRT1SIRT2SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527764-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | Beecham Group p.l.c. (GB) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991015507-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | disclosed |