Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759771 | 0.84 | NR4A2 (0.50) | CA1CA2CA9IDO1AGXT | |
| SCHEMBL7222950 | 0.82 | RXRA (0.45) | ALDH1A1RAB9ANPC1KMT2AUSP2 | |
| SCHEMBL9358412 | 0.82 | MAOA (0.51) | CA1CA2CA9IDO1AGXT | |
| SCHEMBL7221565 | 0.82 | RAB9A (0.50) | CA1CA2CA9AGXTALDH1A1 | |
| SCHEMBL5282539 | 0.82 | IDO1 (0.45) | IDO1AGXTNR4A2GRM5MMP2 | |
| SCHEMBL7664334 | 0.82 | ADAMTS5 (0.52) | NR4A2ALDH1A1GRM5RAB9ANPC1 | |
| SCHEMBL73270 | 0.82 | ALDH1A1 (0.59) | ALDH1A1GRM5RAB9ANPC1KMT2A | |
| SCHEMBL30984464 | 0.81 | CA1 (0.46) | CA1CA2CA9IDO1AGXT | |
| SCHEMBL11334466 | 0.79 | PPARG (0.54) | CA1CA2CA9IDO1AGXT | |
| SCHEMBL30984468 | 0.79 | CA1 (0.45) | CA1CA2CA9IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400489-A | Preparation method of meclofenoxate hydrochloride | 广东华南药业集团有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-109400489-A | Preparation method of meclofenoxate hydrochloride | 广东华南药业集团有限公司 | 2019-03-01 | — | — | CN | disclosed |