SCHEMBL343578

SCHEMBL343578

O=C(Cl)COCCOCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
TSHR P16473 1/20 0.50
NAAA Q02083 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
HTT P42858 1/20 0.46
LMNA P02545 1/20 0.44
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A3 Q01959 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
GRM5 P41594 3/20 0.42
EPHX2 P34913 2/20 0.42
SLC1A1 P43005 1/20 0.41
TEAD3 Q99594 1/20 0.40
NPC1 O15118 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL73270 0.90 ALDH1A1 (0.59) ALDH1A1TSHRMAPK1L3MBTL1SLC6A2
SCHEMBL11907139 0.86 ALDH1A1 (0.56) ALDH1A1TSHRSMN1; SMN2LMNAMAPK1
SCHEMBL1956559 0.85 TSHR (0.54) ALDH1A1TSHRNAAASMN1; SMN2HTT
SCHEMBL21962241 0.85 TSHR (0.54) ALDH1A1TSHRNAAASMN1; SMN2HTT
SCHEMBL3257614 0.83 TDP1 (0.48) ALDH1A1TSHRSMN1; SMN2LMNAMAPK1
SCHEMBL2639772 0.83 ALDH1A1 (0.55) ALDH1A1TSHRSMN1; SMN2HTTLMNA
SCHEMBL4963940 0.83 NAAA (0.53) ALDH1A1TSHRNAAASMN1; SMN2HTT
SCHEMBL4966266 0.83 NAAA (0.53) ALDH1A1TSHRNAAASMN1; SMN2HTT
SCHEMBL3543002 0.83 NAAA (0.53) ALDH1A1TSHRNAAASMN1; SMN2HTT
SCHEMBL2469408 0.83 NAAA (0.53) ALDH1A1TSHRNAAASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333424-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2025-10-30 US disclosed
US-RE46234-E1 Tissue adhesive and sealant comprising polyglycerol aldehyde ACTAMAX SURGICAL MATERIALS, LLC (US) 2016-12-13 US disclosed
US-8846845-B2 Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices BEZWADA BIOMEDICAL, LLC (US) 2014-09-30 US disclosed
EP-2411062-B1 TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE ACTAMAX SURGICAL MATERIALS LLC (US) 2014-08-20 EP disclosed
US-8802892-B2 Functionalized phenolic compounds and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-8680200-B2 Polyglycerol aldehydes ACTAMAX SURGICAL MATERIALS LLC (US) 2014-03-25 US disclosed
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
US-20130281652-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC 2013-10-24 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-8436201-B2 Functionalized diphenolics and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-05-07 US disclosed
US-7935843-B2 Functionalized diphenolics and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-05-03 US disclosed
US-7858077-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC (US) 2010-12-28 US disclosed
US-20100260702-A1 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES BEZWADA BIOMEDICAL LLC (US) 2010-10-14 US disclosed
WO-2010111570-A1 POLYGLYCEROL ALDEHYDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-30 WO disclosed
WO-2010111594-A1 TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-30 WO disclosed
US-7772352-B2 Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices BEZWADA BIOMEDICAL LLC (US) 2010-08-10 US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
US-20070135355-A1 FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-14 US disclosed
US-20070129787-A1 DIFUNCTIONALIZED AROMATIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135355-A1 FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM DDT, DHCR7, NOTUM ALDH1A1 905/4885TSHR 4433/4885NAAA 2478/4885
US-20100260702-A1 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES ALOX12, HAO2, ALOX15 ALDH1A1 219/4885TSHR 3143/4885NAAA 1510/4885
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM COMT, AOX1, UGT1A6 ALDH1A1 384/4885TSHR 4541/4885NAAA 4092/4885
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 ALDH1A1 1912/4885TSHR 3176/4885NAAA 1803/4885
US-20250333424-A1 ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, IRF3 ALDH1A1 3515/4885TSHR 4788/4885NAAA 3080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.