Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 8/20 | 0.40 |
| ▸ | CTSK | P43235 | 8/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329784 | 0.90 | CTSB (0.42) | CTSBCTSKSIRT2SIRT1SIRT3 | |
| SCHEMBL7331320 | 0.89 | CTSB (0.40) | CTSBCTSKSIRT2SIRT1SIRT3 | |
| SCHEMBL7332898 | 0.85 | CTSD (0.33) | CTSD | |
| SCHEMBL7324481 | 0.85 | CAPN1 (0.36) | CTSKSIRT2SIRT1CAPN1CAPN2 | |
| SCHEMBL7329206 | 0.81 | CTSB (0.42) | CTSBCTSKSIRT2SIRT1SIRT3 | |
| SCHEMBL7323250 | 0.76 | SOAT1 (0.37) | SIRT2SIRT1SIRT3CAPN1CAPN2 | |
| SCHEMBL7323662 | 0.76 | CTSD (0.34) | SIRT2SIRT1SIRT3CTSD | |
| SCHEMBL7330215 | 0.75 | CTSL (0.41) | CTSKSIRT2SIRT1SIRT3CAPN1 | |
| SCHEMBL7322416 | 0.75 | CTSD (0.35) | RENSOAT1CTSD | |
| SCHEMBL7326622 | 0.72 | CTSB (0.41) | CTSBCTSKSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |