Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 8/20 | 0.42 |
| ▸ | CTSK | P43235 | 8/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331046 | 0.84 | CTSD (0.33) | SOAT1CERT1 | |
| SCHEMBL7331320 | 0.83 | CTSB (0.40) | CTSBCTSKSIRT2SIRT1SIRT3 | |
| SCHEMBL7319638 | 0.83 | CTSK (0.46) | CTSBCTSKCAPN1CAPN2 | |
| SCHEMBL7327305 | 0.81 | CTSB (0.40) | CTSBCTSKSIRT2SIRT1SIRT3 | |
| SCHEMBL7332552 | 0.79 | CTSD (0.34) | SOAT1CERT1 | |
| SCHEMBL7323322 | 0.78 | LPAR1 (0.35) | — | |
| SCHEMBL7326622 | 0.78 | CTSB (0.41) | CTSBCTSKSIRT2SIRT1SIRT3 | |
| SCHEMBL7329554 | 0.78 | SIRT2 (0.35) | CTSBCTSKSIRT2SIRT1SIRT3 | |
| SCHEMBL7329784 | 0.78 | CTSB (0.42) | CTSBCTSKSIRT2SIRT1SIRT3 | |
| SCHEMBL7328933 | 0.77 | SOAT1 (0.37) | SIRT2SIRT1SIRT3SOAT1CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |