Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195776 | 1.00 | CASP1 (0.69) | CASP1 | |
| SCHEMBL19067195 | 0.89 | CASP1 (0.57) | CASP1 | |
| SCHEMBL7327386 | 0.87 | TACR1 (0.62) | — | |
| SCHEMBL6330507 | 0.87 | TACR1 (0.62) | — | |
| SCHEMBL27544004 | 0.87 | CASP3 (0.59) | CASP1 | |
| SCHEMBL27544008 | 0.87 | CASP3 (0.59) | CASP1 | |
| SCHEMBL9069236 | 0.86 | CASP1 (0.59) | CASP1 | |
| SCHEMBL21057770 | 0.86 | CASP1 (0.69) | CASP1 | |
| SCHEMBL4280674 | 0.85 | CASP1 (0.67) | CASP1 | |
| SCHEMBL4280669 | 0.85 | CASP1 (0.67) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215559-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | ARIA PHARMACEUTICALS, INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| WO-2001019373-A2 | METHODS AND COMPOSITIONS FOR MODULATING RESPONSIVENESS TO CORTICOSTEROIDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |
| CN-1269722-A | Method and composition for modulating responsiveness to corticosteroids | BASF AG (DE) | 2000-10-11 | — | — | CN | disclosed |
| EP-0998300-A1 | METHODS AND COMPOSITIONS FOR MODULATING RESPONSIVENESS TO CORTICOSTEROIDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-10 | — | — | EP | disclosed |
| WO-1998041232-A2 | COMPOSITIONS FOR MODULATING RESPONSIVENESS TO CORTICOSTEROIDS | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-24 | — | — | WO | disclosed |