SCHEMBL7327405 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	PPARG	P37231	1/20	0.38

▸	MMP2	P08253	4/20	0.37

▸	HDAC3	O15379	13/20	0.36

▸	HDAC4	P56524	13/20	0.36

▸	HDAC1	Q13547	13/20	0.36

▸	HDAC7	Q8WUI4	13/20	0.36

▸	HDAC2	Q92769	13/20	0.36

▸	HDAC10	Q969S8	13/20	0.36

▸	HDAC11	Q96DB2	13/20	0.36

▸	HDAC8	Q9BY41	13/20	0.36

▸	HDAC6	Q9UBN7	13/20	0.36

▸	HDAC9	Q9UKV0	13/20	0.36

▸	HDAC5	Q9UQL6	13/20	0.36

▸	NOS2	P35228	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Trifluoroacetic Acid SCHEMBL7328417	0.95	PPARG (0.37)	PPARGMMP2HDAC3HDAC4HDAC1
SCHEMBL7324926	0.83	NOS2 (0.51)	PPARGNOS2
SCHEMBL7321906	0.83	MMP2 (0.43)	PPARGMMP2HDAC3HDAC4HDAC1
SCHEMBL7318683	0.83	MMP2 (0.43)	PPARGMMP2HDAC3HDAC4HDAC1
SCHEMBL7322068	0.81	PPARG (0.47)	PPARGMMP2NOS2
SCHEMBL7324333	0.80	NOS3 (0.45)	MMP2NOS2
SCHEMBL7329586	0.79	HDAC3 (0.60)	HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL7328374	0.79	SMN1; SMN2 (0.46)	MMP2NOS2
SCHEMBL7330015	0.79	MMP2 (0.42)	PPARGMMP2
Trifluoroacetic Acid SCHEMBL7327858	0.78	MMP2 (0.41)	PPARGMMP2NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1992018117-A1	ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES	RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US)	1992-10-29	—	—	WO	disclosed