Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | LDHB | P07195 | 1/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308537 | 0.92 | ALOX5 (0.56) | RIPK1ALOX5ALDH1A1KDM4EHTT | |
| SCHEMBL27431296 | 0.83 | MAPT (0.56) | ALOX5LDHALDHBHAO1ALDH1A1 | |
| SCHEMBL2806112 | 0.82 | HTT (0.50) | RIPK1ALOX5LDHALDHBHAO1 | |
| SCHEMBL1642904 | 0.82 | HTT (0.50) | RIPK1ALOX5LDHALDHBHAO1 | |
| Ammonia Solution, Strong SCHEMBL23877941 | 0.81 | HTT (0.49) | RIPK1ALOX5LDHALDHBHAO1 | |
| Nitric Acid SCHEMBL30544994 | 0.77 | RIPK1 (0.46) | RIPK1ALOX5LDHALDHBHAO1 | |
| SCHEMBL29958592 | 0.75 | KDM4E (0.49) | RIPK1ALOX5LDHALDHBHAO1 | |
| SCHEMBL8628856 | 0.75 | TRPM8 (0.49) | RIPK1ALOX5ALDH1A1POLBMEN1 | |
| SCHEMBL14524651 | 0.75 | CA12 (0.48) | RIPK1ALOX5ALDH1A1POLBKDM4E | |
| SCHEMBL3573494 | 0.75 | TRPM8 (0.52) | ALDH1A1POLBTRPM8TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5221665-A | N-substituted amides | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0369391-A2 | N-substituted amides | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1990-05-23 | — | — | EP | disclosed |