Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330316 | 0.95 | SOAT1 (0.31) | SOAT1 | |
| SCHEMBL7331182 | 0.93 | SOAT1 (0.32) | SOAT1 | |
| SCHEMBL7324588 | 0.92 | CTSD (0.32) | — | |
| SCHEMBL7323558 | 0.89 | SIRT2 (0.33) | PPARA | |
| SCHEMBL7329554 | 0.86 | SIRT2 (0.35) | SOAT1MMEACECPA1ACE2 | |
| SCHEMBL7332552 | 0.86 | CTSD (0.34) | SOAT1 | |
| SCHEMBL7333687 | 0.84 | SIRT2 (0.32) | — | |
| SCHEMBL9296616 | 0.81 | CA2 (0.34) | — | |
| SCHEMBL7332120 | 0.81 | SIRT2 (0.33) | PPARA | |
| SCHEMBL7331046 | 0.81 | CTSD (0.33) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |