Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.32 |
| ▸ | CTSD | P07339 | 7/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323558 | 0.96 | SIRT2 (0.33) | SIRT2SIRT1SIRT3LNPEPERAP2 | |
| SCHEMBL7332120 | 0.93 | SIRT2 (0.33) | SIRT2SIRT1SIRT3MEN1KMT2A | |
| SCHEMBL7330316 | 0.89 | SOAT1 (0.31) | CTSD | |
| SCHEMBL7326622 | 0.86 | CTSB (0.41) | SIRT2SIRT1SIRT3CTSBCTSK | |
| SCHEMBL7328766 | 0.84 | SOAT1 (0.31) | — | |
| SCHEMBL7323101 | 0.84 | SIRT2 (0.33) | SIRT2SIRT1SIRT3MEN1KMT2A | |
| SCHEMBL9297056 | 0.83 | SIRT2 (0.34) | SIRT2SIRT1SIRT3MEN1KMT2A | |
| SCHEMBL9296616 | 0.83 | CA2 (0.34) | CTSDLNPEPERAP2MEN1KMT2A | |
| SCHEMBL7323662 | 0.81 | CTSD (0.34) | SIRT2SIRT1SIRT3CTSDLNPEP | |
| SCHEMBL7331504 | 0.81 | SIRT2 (0.38) | SIRT2SIRT1SIRT3CTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |