Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323628 | 0.91 | SIRT2 (0.33) | SIRT2SIRT1CTSBCTSKTLR2 | |
| SCHEMBL7328766 | 0.86 | SOAT1 (0.31) | SOAT1MMEACECPA1ACE2 | |
| SCHEMBL7331504 | 0.86 | SIRT2 (0.38) | SIRT2SIRT1CTSBCTSKMEN1 | |
| SCHEMBL7328933 | 0.85 | SOAT1 (0.37) | SIRT2SOAT1SIRT1HDAC3HDAC4 | |
| SCHEMBL7330316 | 0.81 | SOAT1 (0.31) | SOAT1 | |
| SCHEMBL7326622 | 0.81 | CTSB (0.41) | SIRT2SIRT1CTSBCTSKMEN1 | |
| SCHEMBL9297033 | 0.79 | CTSB (0.42) | SIRT2CTSBCTSKMEN1KMT2A | |
| SCHEMBL7324588 | 0.79 | CTSD (0.32) | — | |
| SCHEMBL7331182 | 0.78 | SOAT1 (0.32) | SOAT1TLR2 | |
| SCHEMBL7319908 | 0.78 | REN (0.37) | SIRT2SIRT1CTSBCTSKCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |