SCHEMBL7330316

SCHEMBL7330316

CCCCCC(=O)N[C@@](C)(C(=O)NC(C(=O)OC)C(C)C)C(CO)CNC(=O)[C@H](C)N(C(=O)OCc1ccccc1-c1ccccc1)C(=O)[C@H](C)N

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 2/20 0.31
CTSD P07339 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7328766 0.95 SOAT1 (0.31) SOAT1
SCHEMBL7331182 0.92 SOAT1 (0.32) SOAT1
SCHEMBL7324588 0.92 CTSD (0.32) CTSD
SCHEMBL7333687 0.89 SIRT2 (0.32) CTSD
SCHEMBL9296616 0.86 CA2 (0.34) CTSD
SCHEMBL7331046 0.86 CTSD (0.33) SOAT1CTSD
SCHEMBL7323558 0.84 SIRT2 (0.33)
SCHEMBL7322416 0.83 CTSD (0.35) SOAT1CTSD
SCHEMBL7329554 0.81 SIRT2 (0.35) SOAT1
SCHEMBL7332552 0.81 CTSD (0.34) SOAT1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1990000399-A1 RETROVIRAL PROTEASE BINDING PEPTIDES SMITHKLINE BECKMAN CORPORATION (US) 1990-01-25 WO disclosed
EP-0352000-A2 Retroviral protease binding peptides SMITHKLINE BEECHAM CORPORATION (US) 1990-01-24 EP disclosed