Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 19/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 19/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 19/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 19/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 19/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 19/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 19/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 19/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 19/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 19/20 | 0.56 |
| ▸ | CCKBR | P32239 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329586 | 0.95 | HDAC3 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Trifluoroacetic Acid SCHEMBL7327858 | 0.82 | MMP2 (0.41) | — | |
| SCHEMBL7324926 | 0.82 | NOS2 (0.51) | — | |
| Trifluoroacetic Acid SCHEMBL7328417 | 0.81 | PPARG (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Trifluoroacetic Acid SCHEMBL7323872 | 0.80 | NOS3 (0.46) | — | |
| Trifluoroacetic Acid SCHEMBL7323026 | 0.80 | MMP2 (0.43) | — | |
| Trifluoroacetic Acid SCHEMBL7327233 | 0.79 | TAS1R3 (0.43) | — | |
| Trifluoroacetic Acid SCHEMBL7321554 | 0.79 | MMP2 (0.40) | CCKBR | |
| Trifluoroacetic Acid SCHEMBL7327323 | 0.78 | NPY4R (0.40) | CCKBR | |
| SCHEMBL7321638 | 0.78 | PPARG (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584066-A4 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES. | RHONE POULENC RORER INT (US) | 1994-10-12 | — | — | EP | claimed |
| EP-0584066-A1 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-03-02 | — | — | EP | claimed |
| WO-1992018117-A1 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-10-29 | — | — | WO | claimed |
| EP-0584066-A4 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES. | RHONE POULENC RORER INT (US) | 1994-10-12 | — | — | EP | disclosed |
| EP-0584066-A1 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992018117-A1 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-10-29 | — | — | WO | disclosed |