Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27431539 | 0.86 | HRH3 (0.64) | HRH3LTA4HKMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL27364342 | 0.85 | HRH3 (0.62) | HRH3LTA4HKMT2AMEN1LMNA | |
| SCHEMBL7330709 | 0.83 | LTA4H (0.61) | HRH3LTA4HLMNATSHRPSMB1 | |
| SCHEMBL7327720 | 0.81 | KDM4E (0.53) | HRH3KMT2AMEN1TSHRSLC6A4 | |
| SCHEMBL7325617 | 0.75 | MAOB (0.53) | HRH3LMNAHTTALDH1A1USP2 | |
| SCHEMBL22564675 | 0.74 | KMT2A (0.46) | HRH3KMT2AMEN1SLC6A4ALDH1A1 | |
| SCHEMBL20663279 | 0.74 | KMT2A (0.46) | HRH3KMT2AMEN1SLC6A4ALDH1A1 | |
| SCHEMBL9528301 | 0.74 | HRH3 (0.68) | HRH3LTA4HKMT2AMEN1LMNA | |
| SCHEMBL13698801 | 0.74 | LTA4H (0.87) | HRH3LTA4HKMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL9528330 | 0.73 | HRH3 (0.67) | HRH3LTA4HKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629190-A1 | COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-12-21 | — | — | EP | claimed |
| WO-1993015052-A1 | COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | claimed |