Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | XDH | P47989 | 2/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7329970 | 0.78 | MAOB (0.62) | MAOBHRH3BCHEACHEXDH | |
| SCHEMBL7398784 | 0.77 | HRH3 (0.83) | MAOBHRH3BCHEACHEXDH | |
| SCHEMBL7327720 | 0.77 | KDM4E (0.53) | HRH3SIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7404288 | 0.76 | HRH3 (0.81) | MAOBHRH3BCHEACHEXDH | |
| SCHEMBL7330709 | 0.76 | LTA4H (0.61) | HRH3LMNAMAPT | |
| SCHEMBL7329500 | 0.75 | HRH3 (0.53) | HRH3LMNAUSP2HTTALDH1A1 | |
| SCHEMBL16806176 | 0.73 | LMNA (0.60) | MAOBHRH3BCHEACHEXDH | |
| SCHEMBL1797372 | 0.73 | SIGMAR1 (0.66) | MAOBHRH3BCHEACHEXDH | |
| SCHEMBL1794419 | 0.72 | MAOB (0.68) | MAOBHRH3BCHEACHEXDH | |
| SCHEMBL1797053 | 0.71 | SIGMAR1 (0.65) | MAOBHRH3BCHEACHEXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629190-A1 | COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-12-21 | — | — | EP | claimed |
| WO-1993015052-A1 | COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | claimed |