Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326622 | 0.95 | CTSB (0.41) | SIRT2SIRT1CAPN1CAPN2CTSL | |
| SCHEMBL7321181 | 0.92 | SIRT2 (0.39) | SIRT2SIRT1CAPN1CAPN2CTSL | |
| SCHEMBL7319908 | 0.92 | REN (0.37) | SIRT2SIRT1CAPN1CAPN2CTSB | |
| SCHEMBL7329554 | 0.86 | SIRT2 (0.35) | SIRT2SIRT1CAPN1CAPN2CTSB | |
| SCHEMBL7323558 | 0.86 | SIRT2 (0.33) | SIRT2SIRT1CAPN1CAPN2SIRT3 | |
| SCHEMBL7323289 | 0.84 | CTSL (0.41) | SIRT2SIRT1CAPN1CAPN2CTSL | |
| SCHEMBL9296873 | 0.82 | SIRT2 (0.40) | SIRT2SIRT1CAPN1CAPN2CTSL | |
| SCHEMBL7333687 | 0.81 | SIRT2 (0.32) | SIRT2SIRT1CTSBCTSKSIRT3 | |
| SCHEMBL9296340 | 0.80 | CTSB (0.42) | SIRT2SIRT1CAPN1CAPN2CTSL | |
| SCHEMBL7332120 | 0.79 | SIRT2 (0.33) | SIRT2SIRT1CAPN1CAPN2SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |