Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.46 |
| ▸ | HRH1 | P35367 | 6/20 | 0.44 |
| ▸ | HRH2 | P25021 | 3/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401781 | 0.84 | HRH3 (0.51) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL7332012 | 0.83 | HRH3 (0.48) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL7330413 | 0.82 | ITGB3 (0.47) | ITGB3ITGA2BHRH3PPARGPRKD1 | |
| SCHEMBL7401777 | 0.81 | PPARG (0.45) | ITGB3ITGA2BHRH3PPARGPPARA | |
| SCHEMBL7402995 | 0.77 | NPY2R (0.43) | ITGB3ITGA2BHRH3PRKD1HTR1A | |
| SCHEMBL7330427 | 0.76 | PPARG (0.45) | ITGB3ITGA2BHRH3PPARGPPARA | |
| SCHEMBL8635826 | 0.73 | HRH3 (0.54) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| Hydrochloric Acid SCHEMBL8681084 | 0.72 | HRH3 (0.53) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL8683408 | 0.72 | CHKA (0.45) | — | |
| SCHEMBL7403779 | 0.71 | ITGB3 (0.58) | ITGB3ITGA2BHRH3HRH1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| EP-0691959-A1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-17 | — | — | EP | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |
| WO-1994022834-A1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |