Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 3/20 | 0.33 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330442 | 0.82 | ANPEP (0.45) | PSMB5MEN1KMT2A | |
| SCHEMBL7331112 | 0.72 | CTSD (0.43) | MEN1KMT2A | |
| SCHEMBL7325941 | 0.67 | BACE1 (0.44) | TSHRMETAP2HPGDRENMETAP1 | |
| SCHEMBL7359932 | 0.67 | METAP2 (0.51) | METAP2RENMETAP1 | |
| SCHEMBL8175196 | 0.67 | METAP2 (0.55) | METAP2RENMETAP1 | |
| SCHEMBL7328407 | 0.67 | METAP2 (0.55) | METAP2RENMETAP1 | |
| Hydrochloric Acid SCHEMBL9514519 | 0.65 | METAP2 (0.53) | METAP2RENMETAP1 | |
| Hydrochloric Acid SCHEMBL9514516 | 0.65 | METAP2 (0.53) | METAP2RENMETAP1 | |
| SCHEMBL10378262 | 0.64 | TSHR (0.52) | TSHRHPGDPADI1PADI4PSMB5 | |
| SCHEMBL27282300 | 0.64 | TSHR (0.52) | TSHRHPGDPADI1PADI4PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |