SCHEMBL7330918

SCHEMBL7330918

O=c1c2cc(O)c(O)cc2oc2c(O)c(O)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE P12821 2/20 1.00
ATP1A1 P05023 3/20 0.70
ATP1B1 P05026 3/20 0.70
ATP1A3 P13637 3/20 0.70
ATP1B2 P14415 3/20 0.70
ATP1A2 P50993 3/20 0.70
ATP1B3 P54709 3/20 0.70
FXYD2 P54710 3/20 0.70
ATP1A4 Q13733 3/20 0.70
NUDT1 P36639 1/20 0.70
PTGS2 P35354 1/20 0.66
PKLR P30613 1/20 0.60
GALNT2 Q10471 1/20 0.60
GALNT1 Q10472 1/20 0.60
GALNT3 Q14435 1/20 0.60
GALNT10 Q86SR1 1/20 0.60
GALNT13 Q8IUC8 1/20 0.60
GALNT6 Q8NCL4 1/20 0.60
GALNT14 Q96FL9 1/20 0.60
MET P08581 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL7338419 0.92 ACE (0.85) ACEATP1A1ATP1B1ATP1A3ATP1B2
SCHEMBL152329 0.85 ACE (0.73) ACEATP1A1ATP1B1ATP1A3ATP1B2
SCHEMBL30451609 0.83 ATP1A1 (1.00) ACEATP1A1ATP1B1ATP1A3ATP1B2
SCHEMBL1444851 0.83 ATP1A1 (1.00) ACEATP1A1ATP1B1ATP1A3ATP1B2
SCHEMBL7227954 0.81 ATP1A1 (0.79) ACEATP1A1ATP1B1ATP1A3ATP1B2
3,4-Dihydroxyxanthone SCHEMBL30668688 0.79 PTGS2 (1.00) ACEATP1A1ATP1B1ATP1A3ATP1B2
3,4-Dihydroxyxanthone SCHEMBL133422 0.79 PTGS2 (1.00) ACEATP1A1ATP1B1ATP1A3ATP1B2
SCHEMBL2318335 0.79 MAOA (0.66) ACEPKLRMCL1MAOAKDM4E
SCHEMBL28990262 0.79 ACE (0.64) ACEATP1A1ATP1B1ATP1A3ATP1B2
SCHEMBL2313484 0.76 ATP1A1 (1.00) ACEATP1A1ATP1B1ATP1A3ATP1B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5495005-A ANTICOAGULANTS, CARDIOVASCULAR DISORDERS NATIONAL SCIENCE COUNCIL (TW) 1996-02-27 US disclosed