Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 1.00 |
| ▸ | ATP1A1 | P05023 | 3/20 | 0.70 |
| ▸ | ATP1B1 | P05026 | 3/20 | 0.70 |
| ▸ | ATP1A3 | P13637 | 3/20 | 0.70 |
| ▸ | ATP1B2 | P14415 | 3/20 | 0.70 |
| ▸ | ATP1A2 | P50993 | 3/20 | 0.70 |
| ▸ | ATP1B3 | P54709 | 3/20 | 0.70 |
| ▸ | FXYD2 | P54710 | 3/20 | 0.70 |
| ▸ | ATP1A4 | Q13733 | 3/20 | 0.70 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.70 |
| ▸ | MAOA | P21397 | 9/20 | 0.70 |
| ▸ | ACE | P12821 | 2/20 | 0.66 |
| ▸ | KDM5A | P29375 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3,4-Dihydroxyxanthone SCHEMBL30668688 | 1.00 | PTGS2 (1.00) | PTGS2ATP1A1ATP1B1ATP1A3ATP1B2 | |
| Xanthone SCHEMBL3616855 | 0.87 | PTGS2 (0.76) | PTGS2ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL3881176 | 0.85 | PTGS2 (0.74) | PTGS2ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL24120562 | 0.83 | PTGS2 (0.71) | PTGS2MAOAKDM5AKDM4EMAPT | |
| SCHEMBL9835933 | 0.83 | PTGS2 (0.71) | PTGS2MAOAKDM5AKDM4EMAPT | |
| SCHEMBL9836624 | 0.83 | PTGS2 (0.71) | PTGS2MAOAKDM5AKDM4EMAPT | |
| SCHEMBL1444851 | 0.83 | ATP1A1 (1.00) | PTGS2ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL30451609 | 0.83 | ATP1A1 (1.00) | PTGS2ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL1788224 | 0.82 | MAOA (1.00) | PTGS2ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL149545 | 0.81 | MAOA (0.73) | PTGS2ATP1A1ATP1B1ATP1A3ATP1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030891-B2 | Xanthonic compounds and their use as antifouling agents | CIIMAR—CENTRO INTERDISCIPLINAR DE INVESTIGACAO MARINHA E AMBIENTAL (PT) | 2024-07-09 | — | — | US | claimed |
| CN-113226035-B | Xanthene compounds and their use as antifouling agents | 海洋与环境研究交叉学科中心 | 2023-10-31 | — | — | CN | claimed |
| US-20210395264-A1 | XANTHONIC COMPOUNDS AND THEIR USE AS ANTIFOULING AGENTS | FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA (PT) | 2021-12-23 | — | — | US | claimed |
| CN-113226035-A | Xanthene compounds and their use as antifouling agents | 海洋与环境研究交叉学科中心 | 2021-08-06 | — | — | CN | claimed |
| CN-107445970-B | DMXAA-pyraloxanthone hybrid compound and preparation method and application thereof | 广州药本君安医药科技股份有限公司 | 2020-02-07 | — | — | CN | claimed |
| US-20150272923-A1 | Na/K-ATPase Ligands, Ouabain Antagonists, Assays and Uses Thereof | THE UNIVERSITY OF TOLEDO (US) | 2015-10-01 | — | — | US | claimed |
| US-20140031419-A1 | Na/K-ATPase Ligands, Ouabain Antagonists, Assays and Uses Thereof | THE UNIVERSITY OF TOLEDO (US) | 2014-01-30 | — | — | US | claimed |
| US-20100137421-A1 | SMALL MOLECULE THERAPEUTICS, SYNTHESIS OF ANALOGUES AND DERIVATIVES AND METHODS OF USE | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2010-06-03 | — | — | US | claimed |
| WO-2008057604-A9 | SMALL MOLECULE THERAPEUTICS, SYNTHESES OF ANALOGUES AND DERIVATIVES AND METHODS OF USE | UNIV CALIFORNIA (US) | 2008-10-02 | — | — | WO | claimed |
| WO-2008057604-A2 | SMALL MOLECULE THERAPEUTICS, SYNTHESES OF ANALOGUES AND DERIVATIVES AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-05-15 | — | — | WO | claimed |
| US-5741813-A | ADMINISTERING SUBSTITUTED XANTHONES | NATIONAL SCIENCE COUNCIL (TW) | 1998-04-21 | — | — | US | claimed |
| US-12030891-B2 | Xanthonic compounds and their use as antifouling agents | CIIMAR—CENTRO INTERDISCIPLINAR DE INVESTIGACAO MARINHA E AMBIENTAL (PT) | 2024-07-09 | — | — | US | disclosed |
| CN-113226035-B | Xanthene compounds and their use as antifouling agents | 海洋与环境研究交叉学科中心 | 2023-10-31 | — | — | CN | disclosed |
| US-20210395264-A1 | XANTHONIC COMPOUNDS AND THEIR USE AS ANTIFOULING AGENTS | FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA (PT) | 2021-12-23 | — | — | US | disclosed |
| US-20210395264-A1 | XANTHONIC COMPOUNDS AND THEIR USE AS ANTIFOULING AGENTS | FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA (PT) | 2021-12-23 | — | — | US | disclosed |
| EP-1620564-A2 | METHODS OF TREATING DISEASES RESPONSIVE TO INDUCTION OF APOPTOSIS AND SCREENING ASSAYS | Cytovia, Inc. (US) | 2006-02-01 | — | — | EP | disclosed |
| US-20050004026-A1 | Methods of treating diseases responsive to induction of Apoptosis and screening assays | CYTOVIA, INC. | 2005-01-06 | — | — | US | disclosed |
| WO-2004094647-A2 | METHODS OF TREATING DISEASES RESPONSIVE TO INDUCTION OF APOPTOSIS AND SCREENING ASSAYS | CYTOVIA, INC. (US) | 2004-11-04 | — | — | WO | disclosed |
| US-5741813-A | ADMINISTERING SUBSTITUTED XANTHONES | NATIONAL SCIENCE COUNCIL (TW) | 1998-04-21 | — | — | US | disclosed |
| US-5495005-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | NATIONAL SCIENCE COUNCIL (TW) | 1996-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137421-A1 | SMALL MOLECULE THERAPEUTICS, SYNTHESIS OF ANALOGUES AND DERIVATIVES AND METHODS OF USE | BAD, CASP3, BID | PTGS2 855/4885ATP1A1 4675/4885ATP1B1 4425/4885 |
| US-20050004026-A1 | Methods of treating diseases responsive to induction of Apoptosis and screening assays | HEATR6, HEATR1, AIP | PTGS2 2093/4885ATP1A1 2281/4885ATP1B1 2555/4885 |
| US-20150272923-A1 | Na/K-ATPase Ligands, Ouabain Antagonists, Assays and Uses Thereof | ATP1A2, ATP1B1, ATP1A1 | PTGS2 3533/4885ATP1A1 3/4885ATP1B1 2/4885 |
| US-20140031419-A1 | Na/K-ATPase Ligands, Ouabain Antagonists, Assays and Uses Thereof | ATP1A2, ATP1B1, ATP1A1 | PTGS2 3533/4885ATP1A1 3/4885ATP1B1 2/4885 |
| US-20210395264-A1 | XANTHONIC COMPOUNDS AND THEIR USE AS ANTIFOULING AGENTS | PGLS, Q6ZSR9, ALG1 | PTGS2 3074/4885ATP1A1 3994/4885ATP1B1 3493/4885 |
| US-12030891-B2 | Xanthonic compounds and their use as antifouling agents | PGLS, Q6ZSR9, ALG1 | PTGS2 3074/4885ATP1A1 3994/4885ATP1B1 3493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.