Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078805 | 0.86 | TSHR (0.43) | TSHRALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL7366389 | 0.86 | TSHR (0.43) | TSHRALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL8468700 | 0.83 | ALDH1A1 (0.43) | TSHRALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL7079518 | 0.81 | TSHR (0.36) | TSHRALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL7919242 | 0.71 | TSHR (0.43) | TSHRALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL7401266 | 0.71 | TSHR (0.43) | TSHRALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL7444030 | 0.71 | HPGD (0.43) | TSHRALDH1A1KDM4ETDP1ITGB3 | |
| SCHEMBL23535782 | 0.71 | LMNA (0.49) | ALDH1A1KDM4EPOLBL3MBTL1TDP1 | |
| SCHEMBL30040376 | 0.71 | LMNA (0.49) | ALDH1A1KDM4EPOLBL3MBTL1TDP1 | |
| SCHEMBL6676454 | 0.70 | ITGB3 (0.60) | ALDH1A1KDM4ETDP1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | disclosed |