Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 12/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334079 | 0.80 | FDPS (0.50) | FDPSPTPN1PTPRCTSHRPGK1 | |
| SCHEMBL7340340 | 0.78 | FDPS (0.45) | FDPSPTPN1PTPRCTSHRPGK1 | |
| SCHEMBL21822083 | 0.77 | FDPS (0.47) | FDPSPTPN1MEN1CYP1A2KMT2A | |
| SCHEMBL6741779 | 0.70 | PPARG (0.51) | PTPN1CYP1A2TSHR | |
| SCHEMBL16754032 | 0.70 | PPARG (0.51) | PTPN1CYP1A2TSHR | |
| SCHEMBL10626908 | 0.70 | FDPS (0.61) | FDPSPTPN1MEN1CYP1A2KMT2A | |
| SCHEMBL7603206 | 0.68 | FDPS (0.59) | FDPSPTPN1CYP1A2TSHRTRPA1 | |
| SCHEMBL4098286 | 0.68 | PTPN5 (0.32) | — | |
| SCHEMBL9849577 | 0.68 | FDPS (0.58) | FDPSPTPN1PTPRCPGK1PGK2 | |
| SCHEMBL7340346 | 0.68 | LAP3 (0.42) | MEN1CYP1A2KMT2ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952327-A | NEUTRAL ENDOPEPTIDASE INHIBITORS; TREATMENT OF CARDIOVASCULAR DISORDERS | SOLVAY PHARMACEUTICALS GMBH (DE) | 1999-09-14 | — | — | US | disclosed |