Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 12/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.40 |
| ▸ | PGK1 | P00558 | 2/20 | 0.36 |
| ▸ | PGK2 | P07205 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334079 | 0.91 | FDPS (0.50) | FDPSPTPN1PTPRCPGK1PGK2 | |
| SCHEMBL698715 | 0.81 | LPAR1 (0.37) | FDPS | |
| SCHEMBL7333271 | 0.78 | FDPS (0.43) | FDPSPTPN1PTPRCPGK1PGK2 | |
| SCHEMBL6828589 | 0.75 | KMT2A (0.45) | FDPSPTPN1TSHR | |
| SCHEMBL6741779 | 0.72 | PPARG (0.51) | PTPN1CES1TSHR | |
| SCHEMBL16754032 | 0.72 | PPARG (0.51) | PTPN1CES1TSHR | |
| SCHEMBL5324671 | 0.70 | LMNA (0.44) | FDPSPTPN1 | |
| SCHEMBL7263779 | 0.70 | FDPS (0.58) | FDPSPTPN1PTPRCTSHR | |
| SCHEMBL9849577 | 0.70 | FDPS (0.58) | FDPSPTPN1PTPRCPGK1PGK2 | |
| Aniline SCHEMBL2334841 | 0.69 | SLC6A2 (0.42) | CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952327-A | NEUTRAL ENDOPEPTIDASE INHIBITORS; TREATMENT OF CARDIOVASCULAR DISORDERS | SOLVAY PHARMACEUTICALS GMBH (DE) | 1999-09-14 | — | — | US | disclosed |