Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330719 | 0.85 | REN (0.44) | RENPSMB5CPB2CAPN9HDAC4 | |
| SCHEMBL7328043 | 0.84 | CTSK (0.49) | RENPSMB5 | |
| SCHEMBL7371455 | 0.78 | CAPN1 (0.42) | PSMB5CAPN1CTSS | |
| SCHEMBL7326205 | 0.76 | ALDH1A1 (0.46) | RENCPB2NAAAALDH1A1 | |
| SCHEMBL7335551 | 0.76 | CTSK (0.53) | RENPSMB5CAPN1GAAL3MBTL1 | |
| SCHEMBL28564205 | 0.75 | ALDH1A1 (0.47) | CTSSALDH1A1 | |
| SCHEMBL8972235 | 0.75 | ALDH1A1 (0.47) | CTSSALDH1A1 | |
| SCHEMBL7333180 | 0.74 | CTSK (0.41) | PSMB5CAPN1CTSS | |
| SCHEMBL4367034 | 0.74 | ALDH1A1 (0.46) | CTSSALDH1A1 | |
| SCHEMBL7333185 | 0.73 | CAPN1 (0.43) | PSMB5CAPN1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510531-A | ANTIINFLAMMATROY AGENTS, MUSCULAR DISORDERS | SUNTORY LIMITED (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0393457-B1 | Proteinase inhibitor | SUNTORY LTD (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5081284-A | N-Oxomethyl-Substituted Peptide | SUNTORY LIMITED (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0393457-A1 | Proteinase inhibitor | SUNTORY LIMITED (JP) | 1990-10-24 | — | — | EP | disclosed |