Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.49 |
| ▸ | CTSL | P07711 | 6/20 | 0.41 |
| ▸ | CTSB | P07858 | 6/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | CTSH | P09668 | 2/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.37 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330719 | 0.84 | REN (0.44) | RENPSMB5 | |
| SCHEMBL7334255 | 0.84 | REN (0.41) | RENPSMB5 | |
| SCHEMBL7380626 | 0.79 | CTSK (0.59) | CTSKCTSLCTSBPSMB5CTSH | |
| SCHEMBL7324534 | 0.77 | CTSK (0.61) | CTSKCTSLCTSBPSMB5 | |
| SCHEMBL5712420 | 0.76 | CTSK (0.57) | CTSKCTSLCTSBCTSH | |
| SCHEMBL8387889 | 0.76 | CTSK (0.57) | CTSKCTSLCTSBCTSH | |
| SCHEMBL8695376 | 0.76 | CTSK (0.57) | CTSKCTSLCTSBCTSH | |
| SCHEMBL7326205 | 0.76 | ALDH1A1 (0.46) | REN | |
| SCHEMBL8972183 | 0.76 | CTSK (0.57) | CTSKCTSLCTSBCTSH | |
| SCHEMBL7335561 | 0.75 | CTSK (0.60) | CTSKCTSLCTSBPSMB5CTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510531-A | ANTIINFLAMMATROY AGENTS, MUSCULAR DISORDERS | SUNTORY LIMITED (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0393457-B1 | Proteinase inhibitor | SUNTORY LTD (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5081284-A | N-Oxomethyl-Substituted Peptide | SUNTORY LIMITED (JP) | 1992-01-14 | — | — | US | disclosed |