Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | DDX3X | O00571 | 1/20 | 0.49 |
| ▸ | GRK2 | P25098 | 9/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.47 |
| ▸ | GRK3 | P35626 | 6/20 | 0.47 |
| ▸ | GRK5 | P34947 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14625936 | 0.82 | IMPDH2 (0.55) | ROCK2 | |
| SCHEMBL7334697 | 0.81 | GRK2 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8547667 | 0.79 | MEN1 (0.58) | HDAC1DDX3XGRK2ALDH1A1MEN1 | |
| SCHEMBL8547282 | 0.76 | KMT2A (0.56) | HDAC8HDAC6GRK2GRK3ALDH1A1 | |
| SCHEMBL3646757 | 0.75 | ALDH1A1 (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6370197 | 0.75 | DDX3X (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL17560624 | 0.75 | DDX3X (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4518077 | 0.74 | PORCN (0.64) | HDAC1GRK2ALDH1A1ROCK2TAAR1 | |
| SCHEMBL10884504 | 0.73 | DDX3X (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8549861 | 0.73 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |