Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.49 |
| ▸ | ITGAV | P06756 | 15/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951803 | 0.82 | ITGB3 (0.73) | ITGB3ITGAVITGA2BTSHR | |
| SCHEMBL7077881 | 0.79 | ITGB3 (0.73) | ITGB3ITGAVITGA2B | |
| SCHEMBL7659474 | 0.78 | ITGB3 (0.49) | ITGB3ITGAVITGA2BMEN1POLB | |
| SCHEMBL7437624 | 0.77 | ALDH1A1 (0.48) | ITGB3ITGAVITGA2BALDH1A1TDP1 | |
| SCHEMBL8328260 | 0.77 | ALDH1A1 (0.50) | ITGB3ITGAVALDH1A1TDP1MEN1 | |
| SCHEMBL7545780 | 0.75 | ITGB3 (0.59) | ITGB3ITGAVITGA2BKMT2ALMNA | |
| SCHEMBL7541901 | 0.73 | ITGB3 (0.51) | ITGB3ITGAVITGA2BALDH1A1TSHR | |
| SCHEMBL7539970 | 0.72 | ITGB3 (0.46) | ITGB3ITGAVITGA2BTDP1 | |
| SCHEMBL7545503 | 0.72 | ITGB3 (0.47) | ITGB3ITGAVITGA2BLMNA | |
| SCHEMBL15685943 | 0.71 | ALDH1A1 (0.74) | ALDH1A1TDP1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-5977101-A | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | disclosed |